Out-of-plane and in-plane actuation effects on atomic-scale friction

The influence of out-of-plane and in-plane contact vibrations and temperature on the friction force acting on a sharp tip elastically pulled on a crystal surface is studied using a generalized Prandtl- Tomlinson model. The average friction force is significantly lowered in a frequency range determined by the "washboard" frequency of the stick-slip motion and the viscous damping accompanying the tip motion. An approximately linear relation between the actuation amplitude and the effective corrugation of the surface potential is derived in the case of in-plane actuation, extending a similar conclusion for out-of-plane actuation. Temperature causes an additional friction reduction with a scaling relation in formal agreement with the predictions of reaction rate theory in absence of contact vibrations. In this case the actuation effects can be described by the effective energy or, more accurately, by introducing an effective temperature.Comment: To appear in Physical Review

Lateral vibration effects in atomic-scale friction

The influence of lateral vibrations on the stick-slip motion of a nanotip elastically pulled on a flat crystal surface is studied by atomic force microscopy (AFM) measurements on a NaCl(001) surface in ultra-high vacuum. The slippage of the nanotip across the crystal lattice is anticipated at increasing driving amplitude, similarly to what is observed in presence of normal vibrations. This lowers the average friction force, as explained by the Prandtl-Tomlinson model with lateral vibrations superimposed at finite temperature. Nevertheless, the peak values of the lateral force, and the total energy losses, are expected to increase with the excitation amplitude, which may limit the practical relevance of this effect.Comment: To appear in Applied Physics Letter

Anisotropy effects and friction maps in the framework of the 2d PT model

We present a series of numerical simulations on the friction-anisotropy behavior and stick-slip dynamics of a point mass in the framework of a 2d Prandtl-Tomlinson model. Results for three representative surface lattice are shown: square, hexagonal and honeycomb. Curves for scan angle dependence of static friction force, and kinetic one at T=0 K and T=300 K are shown. Friction force maps are computed at different directions.The authors acknowledge financial support from Spanish MINECO through Project no. FIS2011-25167, cofinanced by FEDER funds and Project no. MAT2012-34487. O.Y.F. acknowledges financial support from FPU grant by Ministerio de Ciencia e Inovación of Spain.Peer Reviewe

Electrotunable friction with ionic liquid lubricants: how important is the molecular structure of the ions?

Using non-equilibrium molecular dynamics simulations and a coarse grained model of ionic liquids, we have investigated the impact that the shape and the intramolecular charge distribution of the ions have on the electrotuneable friction with ionic-liquid nanoscale films. We show that the electric-field induces significant structural changes in the film, leading to dramatic modifications of the friction force. Comparison of the present work with previous studies using different models of ionic liquids indicate that the phenomenology presented here applies to a wide range of ionic liquids. In particular, the electric-field-induced shift of the slippage plane from the solid-liquid interface to the interior of the film and the non-monotonic variation of the friction force are common features of ionic lubricants under strong confinement. We also demonstrate that the molecular structure of the ions plays an important role in determining the electrostriction and electroswelling of the confined film, hence showing the importance of ion-specific effects in electrotuneable friction

Manejo de doenças.

324) Quais são as doenças fúngicas mais importantes da macieira? 325) Qual a doença mais grave da macieira no Brasil? 326) As condições climáticas influenciam a severidade da sarna? 327) Como pode ser evitado o aparecimento da sarna? 328) Quais fungicidas são utilizados para controle da sarna? 329) É possível prever o risco de epidemia da sarna? 330) Existem variedades resistentes à sarna? 331) Quais as vantagens do uso de fosfitos para o controle da sarna? 332) Quais são as doenças de verão? 333) Em que época devem ser iniciados os tratamentos para o controle das doenças de verão? 334) A mancha-da-gala ataca todas as variedades? 335) Como a mancha-da-gala se dissemina? 336) É possível prever o período de maior ocorrência da mancha-dagala? 337) Quais os fungicidas utilizados para controle da mancha-da-gala? 338) Quais as principais doenças de frutos antes da colheita? 339) Quais são os sintomas da podridão-amarga? 340) Quais são os sintomas da podridão-olho-de-boi? 341) Quais são os sintomas da podridão-branca? 342) Existe um controle geral para as podridões em fruto? 343) Por que às vezes as maçãs ficam podres internamente? 344) Onde os fungos sobrevivem de uma safra para outra? 345) Qual a importância de fazer os tratamentos de inverno? 346) Qual a importância das doenças virais na cultura da macieira? 347) Quais são os principais vírus da macieira? 348) O que é o declínio? Quando ocorre a morte da planta? 349) Como se reconhece o declínio causado por infecção viral? 350) Os vírus da macieira ocorrem apenas em macieiras? 351) Quais são os danos mais comuns? 352) Como pode ser realizado o controle das viroses? 353) Como se faz a eliminação de vírus das plantas matrizes? 354) Como se faz o diagnóstico de doenças causadas por vírus? 355) Eu mesmo posso fazer o teste biológico de minhas plantas matrizes? 356) Quem faz análises de vírus em macieiras? 357) É possível ?tratar? vírus em plantas de viveiros e pomares? 358) Como são disseminadas as doenças virais da macieira

Isolation of Acanthamoeba Genotype T4 from a Non-Contact Lens Wearer from the Philippines

We report the case of a 76-year old Filipino male who presented with pain, redness, and blurring of vision of the right eye. Corneal scraping was done and sent to the St. Luke’s Research and Biotechnology Group for detection and identification of the infectious agent. Morphological detection was performed by allowing the organism from the scraping to grow in 1.5% non-nutrient agar plate with heat-killed E. coli. Trophozoites with acanthopodia and double-walled cysts characteristic of Acanthamoeba were observed within the first and second week of observations, respectively. Molecular identification of the amoebae at the genus level based on the presence of Acanthamoeba-specific amplimer S1, ASA.S1 confirmed the morphological identification. Genotyping through sequence revealed that the organism belonged to T4, which is the genotype commonly present in the eye of keratitis patients

An early warning method for agricultural products price spike based on artificial neural networks prediction

In general, the agricultural producing sector is affected by the diversity in supply, mostly from small companies, in addition to the rigidity of the demand, the territorial dispersion, the seasonality or the generation of employment related to the rural environment. These characteristics differentiate the agricultural sector from other economic sectors. On the other hand, the volatility of prices payed by producers, the high cost of raw materials, and the instability of both domestic and international markets are factors which have eroded the competitiveness and profitability of the agricultural sector. Because of the advance in technology, applications have been developed based on Artificial Neural Networks (ANN) which have helped the development of sales forecast on consumer products, improving the accuracy of traditional forecasting systems. This research uses the RNA to develop an early warning system for facing the increase in agricultural products, considering macro and micro economic variables and factors related to the seasons of the year

Social sciences research in neglected tropical diseases 2: A bibliographic analysis

The official published version of the article can be found at the link below.Background There are strong arguments for social science and interdisciplinary research in the neglected tropical diseases. These diseases represent a rich and dynamic interplay between vector, host, and pathogen which occurs within social, physical and biological contexts. The overwhelming sense, however, is that neglected tropical diseases research is a biomedical endeavour largely excluding the social sciences. The purpose of this review is to provide a baseline for discussing the quantum and nature of the science that is being conducted, and the extent to which the social sciences are a part of that. Methods A bibliographic analysis was conducted of neglected tropical diseases related research papers published over the past 10 years in biomedical and social sciences. The analysis had textual and bibliometric facets, and focussed on chikungunya, dengue, visceral leishmaniasis, and onchocerciasis. Results There is substantial variation in the number of publications associated with each disease. The proportion of the research that is social science based appears remarkably consistent (<4%). A textual analysis, however, reveals a degree of misclassification by the abstracting service where a surprising proportion of the "social sciences" research was pure clinical research. Much of the social sciences research also tends to be "hand maiden" research focused on the implementation of biomedical solutions. Conclusion There is little evidence that scientists pay any attention to the complex social, cultural, biological, and environmental dynamic involved in human pathogenesis. There is little investigator driven social science and a poor presence of interdisciplinary science. The research needs more sophisticated funders and priority setters who are not beguiled by uncritical biomedical promises

Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering

Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL) and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering. Multilayered constructs were formed by depositing the polyelectrolytes chitosan (CHT) and chondroitin sulphate (CS) on either bidimensional glass surfaces or 3D packet of paraffin spheres. 2D CHT/CS multi-layered constructs proved to support the attachment and proliferation of bovine chondrocytes (BCH). The technology was transposed to 3D level and CHT/CS multi-layered hierarchical scaffolds were retrieved after paraffin leaching. The obtained nanostructured 3D constructs had a high porosity and water uptake capacity of about 300%. Dynamical mechanical analysis (DMA) showed the viscoelastic nature of the scaffolds. Cellular tests were performed with the culture of BCH and multipotent bone marrow derived stromal cells (hMSCs) up to 21 days in chondrogenic differentiation media. Together with scanning electronic microscopy analysis, viability tests and DNA quantification, our results clearly showed that cells attached, proliferated and were metabolically active over the entire scaffold. Cartilaginous extracellular matrix (ECM) formation was further assessed and results showed that GAG secretion occurred indicating the maintenance of the chondrogenic phenotype and the chondrogenic differentiation of hMSCs